News UYSD: a novel data repository accessible via public website for worldwide population frequencies of Y-SNP haplogroups

[Tautalus]

The Universal Y-SNP Database (UYSD) is a newly developed platform that consolidates worldwide population data on Y-SNP haplogroups, making it accessible for researchers studying human genetic diversity, migration, and population genetics. It harmonizes diverse datasets, allowing exploration of global Y-chromosomal variation and facilitating automated haplogroup analysis. UYSD provides an interactive world map that visualizes haplogroup distributions, estimates frequencies in regions with sparse data, and displays detailed phylogenetic trees of Y-chromosomal haplogroups. The dataset currently includes data from just over 6,600 males across 27 populations, which is relatively small for a global-scale genetic repository. The database is still in its early stages, and its creators anticipate expansion as more researchers contribute additional data.​

Abstract

For decades, there has been scientific interest in the variation and geographic distribution of paternal lineages associated with the human Y chromosome. However, the relevant data have been dispersed across numerous publications, making it difficult to consolidate. Additionally, understanding the relationships between different variants, and the tools used to analyze them, have evolved over time, further complicating efforts to harmonize this information. The Universal Y-SNP Database (UYSD) marks a substantial advancement by providing a comprehensive and accessible platform for Y-SNP and haplogroup data from populations around the world. UYSD harmonizes diverse datasets into a unified repository, facilitating the exploration of global Y-chromosomal variation. The platform handles data generated with both high- and low-throughput technology and is compatible with the automated analysis software tool, Yleaf v3. Key functionalities include the ability to: i) visualize haplogroup distributions on an interactive world map, ii) estimate haplogroup frequencies in geographic regions with sparse data through interpolation, and iii) display detailed phylogenetic trees of Y-chromosomal haplogroups. Currently, UYSD encompasses data from over 6,600 males across 27 populations. This dataset largely aligns with known global Y-haplogroup patterns, but also reveals unexplored finer-scale geographic variations. While the present dataset is largely European-centered, UYSD is designed for ongoing expansion by the scientific community, aiming to include more global data and higher-resolution population sequencing data. The platform thus offers valuable insights into human genetic diversity and migration patterns, serving several fields of research such as: human population genetics, genetic anthropology, ancient DNA analysis and forensic genetics.

UYSD: a novel data repository accessible via public website for worldwide population frequencies of Y-SNP haplogroups
​

Welcome

ysnp.erasmusmc.nl

Worldwide distribution of basal Y-haplogroups in the 27 populations currently included in UYSD.

 

[Ricardo]

Just like in FTDNA database, my clade is around 0,5% of the Portuguese samples.

 

[ghazi du]

WOW，